Trials / Unknown
UnknownNCT01949753
Influence of Pregnenolone on Exposure Therapy in Obsessive-compulsive Disorder
Influence of Pregnenolone on Distress and Autonomic Parameters During Cognitive-behavioral Exposure Therapy in Patients With Obsessive-compulsive Disorder
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Characterization of the influence of pregnenolone vs. placebo on subjective distress and autonomic functioning during cognitive-behavioral exposure therapy in patients with obsessive-compulsive disorder.
Detailed description
Main out-come parameters: Inter-session habituation as per SUD (100 mm VAS), Y-BOCS Secondary out-come parameter: HF/LF of HRV, Salivary epinephrine
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Exposure therapy with pharmacological facilitation | Exposure with response prevention and pharmacological facilitation |
| BEHAVIORAL | Exposure therapy | Exposure with response prevention without pharmacological facilitation |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2017-12-01
- Completion
- 2018-12-01
- First posted
- 2013-09-24
- Last updated
- 2017-08-03
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01949753. Inclusion in this directory is not an endorsement.