Trials / Completed
CompletedNCT01949415
An Optional Investigation of Biomarkers of Efficacy
An Optional Investigation of Biomarkers of Efficacy in TH002 Clinical Study Subjects.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 105 (estimated)
- Sponsor
- Circassia Limited · Industry
- Sex
- All
- Age
- 16 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
House Dust Mites (HDM) are arachnids that infest bedding, carpet, upholstered furniture and fabric. Like many other allergens, exposure to HDMA in sensitised patients is associated with poorer lung function, greater medication requirements and more asthma symptoms as well as chronic rhinosinusitis symptoms. In contrast to other allergens, there is evidence that HDMA leads to the development of asthma, in addition to exacerbating pre-existing asthma in HDM-sensitised patients. ToleroMune House Dust Mite (TM-HDM) is being developed for the treatment of HDM allergy. Study TH002 evaluated the efficacy, safety and tolerability of TM-HDM. This study will identify cellular, proteomic or genetic biomarkers of efficacy to TM-HDM treatment in TH002 study participants
Conditions
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2014-04-01
- Completion
- 2014-04-01
- First posted
- 2013-09-24
- Last updated
- 2014-05-21
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT01949415. Inclusion in this directory is not an endorsement.