NCT01946386

A Vasoconstriction Study With LEO 90100

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: LEO Pharma · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the pharmacodynamic activity of LEO 90100 with Dermovate® cream, Dovobet® ointment, betamethasone dipropionate in LEO90100 vehicle, Synalar® ointment and LEO 90100 vehicle using a human skin blanching test.

Conditions

• Psoriasis Vulgaris

Interventions

Type	Name	Description
DRUG	LEO 90100 Aerosol, foam	The products will be applied on 6 test sites (according to random assignment to specific test sites predetermined on their anterior face of forearms) for 6 hours
DRUG	Betamethasone dipropionate in LEO 90100 Aerosol, foam, vehicle
DRUG	LEO 90100 Aerosol, foam, vehicle
DRUG	Daivobet® ointment
DRUG	Dermovate® cream
DRUG	Synalar® ointment

Timeline

• Start date: 2013-09-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2013-09-19
• Last updated: 2025-02-24

Locations

1 site across 1 country: France