NCT01945853

Magnetic Resonance Imaging (MRI) in Amyotrophic Lateral Sclerosis (ALS)

Imaging Myelin Injury in Amyotrophic Lateral Sclerosis (ALS)

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is a pilot study to identify the degree of grey and white matter involvement in patients with Amyotrophic Lateral Sclerosis (ALS) utilizing non-invasive techniques. The imaging to be utilized will be the 7 Tesla (7T) magnetic resonance imaging (MRI) of the brain. These results will be correlated to the ALS Functional Rating Scale - Revised (ALSFRS-R) score to assess if any changes in MRI can be predictive in the disability of the ALS patients at baseline and at 6 month intervals. The participants will be asked to return every 6 months for a neurological examination, ALSFRS-R assessment, measurement of the vital capacity and MRI as outlined above to monitor progression of the disease.

Conditions

• Amyotrophic Lateral Sclerosis (ALS)

Interventions

Type	Name	Description
DEVICE	7 Tesla MRI

Timeline

• Start date: 2013-07-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2013-09-19
• Last updated: 2015-09-01

Locations

1 site across 1 country: United States