NCT01945554

The Value of Short-term Pain Relief for the Prediction of Long-term Outcome After Cervical or Lumbar Nerve Root Infiltration

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: Holger Joswig · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose if this study is to assess the response to nerve root infiltration therapy in patients with cervical or lumbar disc herniations.

Detailed description

This prospective, observational study examines the response to routine infiltration therapy in patients suffering from disc herniations of the spine. Using health-related quality of life questionnaires (SF-12 and Neck Pain and Disability Scale and Oswestry Disability Index) and the visual analogue scale the patients will be categorized into ultra-early-, early-, mid-term-, late-responders and non-responders. A two year follow-up of up to 250 patients is planned. With the anonymized participation of this study no patient will experience a change in his treatment plan. Valuable therapeutic management considerations might be drawn from the published results of this study for future patients.

Conditions

• Cervical Disc Herniation
• Lumbar Disc Herniation

Interventions

Type	Name	Description
PROCEDURE	Cervical nerve root infiltration	4mg Mephamesone followed by 1ml of 0.5% bupivacaine (Bupivacain®) will be administered.
PROCEDURE	Lumbar nerve root infiltration	40mg triamzinolone (Kenacort®) followed by 2ml of 0.5% bupivacaine (Bupivacain®) will be administered.
DRUG	Mephamesone
DRUG	0.5% bupivacaine (Bupivacain®)
DRUG	Kenacort®

Timeline

• Start date: 2013-07-01
• Primary completion: 2017-03-01
• Completion: 2017-03-01
• First posted: 2013-09-18
• Last updated: 2018-01-25

Locations

3 sites across 1 country: Switzerland