Trials / Completed
CompletedNCT01944683
A Double-Blind Pharmacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients With Heart Failure
Phase 1b Study of Pharmacokinetic Interaction, Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients With Heart Failure
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- Acorda Therapeutics · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The study will examine midazolam pharmacokinetics following single dose administration of 3 planned dose levels of GGF2 .
Detailed description
This drug-drug interaction (DDI) study evaluates the potential effect of intravenously administered GGF2 on the elimination kinetics of midazolam.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Placebo | |
| DRUG | GGF2 | |
| DRUG | Midazolam |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2016-05-01
- Completion
- 2016-07-01
- First posted
- 2013-09-18
- Last updated
- 2016-07-13
Locations
8 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01944683. Inclusion in this directory is not an endorsement.