NCT01944488

LH Response to GnRH Test in Prepubescent Girls Under 6 Years

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Aarhus · Academic / Other
• Sex: Female
• Age: 7 Months – 6 Years
• Healthy volunteers: Accepted

Summary

The project aims to establish the normal LH and FSH response to a standardized GnRH dose in healthy girls below 6 years of age, and compares the normal GnRH response to the GnRH response in girls with early puberty development. The novel data may help to determine whether the girl is in early puberty or not. Healthy girls under 6 years of age attending routine examinations including an i.v. line for other causes are included in this study. Our examinations also include bone age determination, Tanner stage determination, and anthropometric measures (height and weight). 10 healthy girls in each of the following age groups: 7-12 months, 12-24 months, 24-36 months, 36-48 months, 48-60 months and 60-72 months are included.

Detailed description

Please refer to the brief summary which covers the study aim, methods and outcome measures.

Conditions

• Precocious Puberty

Interventions

Type	Name	Description
DRUG	GnRH agonist	100 µg/m2 body surface max 100 µg i.v.

Timeline

• Start date: 2013-09-01
• Primary completion: 2014-09-01
• Completion: 2014-09-01
• First posted: 2013-09-17
• Last updated: 2013-09-17

Locations

1 site across 1 country: Denmark