NCT01944215

Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 154 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: Female
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The primary objective of this study is to determine if exercise, fasting, or eating prior to the molecular breast imaging study will have an effect on the uptake of the tracer in the breast tissue.

Detailed description

The primary objective of this study is to determine if exercise, fasting, or eating prior to a molecular breast imaging study will have an effect on the uptake of the radiotracer Tc-99m sestamibi in the breast tissue. Tc-99m sestamibi is primarily extracted by the liver. Changes in hepatic blood flow may therefore influence the amount of radiotracer available for uptake in the breast tissue.

Conditions

• Molecular Imaging

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Meal	effect of meal
OTHER	Exercise	effect of exercise
RADIATION	Sestamibi	reduce radiation dose
DRUG	Caffeine Tablet	effect of caffeine
OTHER	External Heating	Heating Pad and warm blanket robe

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2013-09-17
• Last updated: 2017-04-18

Locations

1 site across 1 country: United States