NCT01941394

Mesenchymal Stem Cells Infusion for aGVHD Prophylaxis Transplantation

Pilot Study for Safety and Effectiveness Assessment of Bone Marrow Mesenchymal Stem Cell Infusion for Acute Graft-versus-host Disease Prophylaxis and Treatment After Allogenic Bone Marrow Transplantation

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: National Research Center for Hematology, Russia · Network
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Infusion of Mesenchymal Stem Cell (MSC) at day of recovery after bone marrow transplant (BMT) for patients with AL, AA and MM for acute Graft-versus-host Disease (GVHD) prophylaxis and treatment.

Detailed description

Infusion of mesenchymal stem cells at day of recovery after BMT for patients with AL, AA and MM for acute GVHD prophylaxis and treatment. Infusion at dose 1 cells mln/kg at day of white blood cells recovery.

Conditions

• Graft-versus-host Disease
• Relapse

Interventions

Type	Name	Description
BIOLOGICAL	Mesenchymal stem cells	Mesenchymal stem cells infusion

Timeline

• Start date: 2007-10-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2013-09-13
• Last updated: 2013-09-13

Locations

1 site across 1 country: Russia