NCT01940263

Purified Anthocyanin and Nonalcoholic Fatty Liver Disease

Effects of Purified Anthocyanin on Oxidative and Inflammatory Markers in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized, Double-Blinded, Placebo-Controlled Trial

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 63 (actual)
• Sponsor: Shaoguan University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Oxidative stress and inflammation are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Anthocyanins from different plant foods have been shown to improve features of experimental NASH, such as oxidative stress, dyslipidemia, liver steatosis, and inflammation in rodents. The purpose of this study is to investigate whether purified anthocyanin supplementation beneficially alters oxidative, inflammatory, and apoptotic biomarkers in adults with features of NAFLD.

Conditions

• Nonalcoholic Fatty Liver Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Anthocyanin
DIETARY_SUPPLEMENT	Placebo

Timeline

• Start date: 2013-06-01
• Primary completion: 2014-01-01
• Completion: 2014-06-01
• First posted: 2013-09-12
• Last updated: 2014-08-01

Locations

1 site across 1 country: China