NCT01939288

Effect of Neuromuscular Calf Stimulation and Intermittent Pneumatic Compression on Lower Limb Venous Hemodynamics

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

What is known? * Disorders of peripheral circulation result in vascular morbidity and mortality * Augmentation of peripheral circulation has been shown to be of benefit in both venous and arterial disease * The benefit of intermittent pneumatic compression is clinically well evidenced. * The use of intermittent pneumatic compression is limited by compliance issues related to sleeve application and external power source. What new information will this trial contribute? \- This evaluates the haemodynamic effect of a new electrical device for augmentation of peripheral circulation

Detailed description

RATIONALE - Enhancement of peripheral circulation has been shown to be of benefit in many vascular disorders, and the clinical effectiveness of intermittent pneumatic compression (IPC) is well established in peripheral vascular disease. OBJECTIVE - This study aims to compare the haemodynamic efficacy of a novel neuromuscular electrical stimulation (NMES) device with IPC in healthy subjects. METHODS - 10 healthy volunteers will be randomised into two groups, in an interventional cross-over trial. Baseline measurements of haemodynamic velocity and flow will be taken, then subjects given bilateral therapy with each of the two devices in turn. Laser doppler fluximetry readings will be taken from the hand and foot. Baseline readings will be compared with readings taken after immediate cessation of therapy, and after 10 minutes. Tolerability will be measured using a verbal reported score.

Conditions

• Intermittent Pneumatic Compression

Interventions

Type	Name	Description
DEVICE	Neuromuscular stimulation, followed by intermittent pneumatic compression
DEVICE	Intermittent pneumatic compression, followed by neuromuscular stimulation

Timeline

• Start date: 2012-12-01
• Primary completion: 2013-12-01
• Completion: 2013-12-01
• First posted: 2013-09-11
• Last updated: 2019-09-20
• Results posted: 2019-07-22

Locations

1 site across 1 country: United Kingdom