NCT01938469

Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: St. Luke's-Roosevelt Hospital Center · Academic / Other
• Sex: All
• Age: 21 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Analyze the effect of meal pattern (meal number, frequency, and form) on satiety, gut peptides, insulin, and glucose levels in individuals before and 12-15 months after gastric bypass surgery (GBP).

Detailed description

The main goal is to study the effect of meal number, size and texture on metabolism and incretin levels after GBP. Patients will be studied before GBP (T0) and 12-15 months after GBP (T1). At T0 and T1, patients will come for 2 study days for 8 hours: On one study day, a single meal will be served, on the second study day, three small isocaloric meals, with the order of the conditions randomly assigned. The total amount of calories and the overall nutrient composition will be equivalent between conditions. The meals will be either all solid or all liquid. Patients enrolled in the study will be randomly assigned to solid or liquid test meals. Gastric emptying will be measured by the acetaminophen test.

Conditions

• Gastric Bypass Surgery
• Obesity

Interventions

Type	Name	Description
OTHER	Liquid Meal
OTHER	Solid Meal

Timeline

• Start date: 2010-09-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2013-09-10
• Last updated: 2016-12-29

Locations

1 site across 1 country: United States