Trials / Unknown
UnknownNCT01938339
Development of Clinical Assessment Technique Using Multi-radiotracer PET/MR in Prostate Cancer
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Seoul National University Hospital · Academic / Other
- Sex
- Male
- Age
- —
- Healthy volunteers
- Not accepted
Summary
To development of clinical assessment technique using multi-radiotracer positron emission tomography/magnetic resonance (PET/MR) in prostate cancer * to establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer * to establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer and early detection of recurrent prostate cancer
Detailed description
To establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer * Recruiting 30 patients with prostate cancer ahead to radical prostatectomy * PET/MR using 18F-choline with dedicated prostate MRI in all patients * PET/MR using 18fluoride(F)-fluorodeoxyglucose(FDG)in all patients after 2-7 days * PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR * outcome assessment: comparison of scan time, image quality, tumor detection rate, standardized uptake values of lesions * establishing optimal imaging technique for prostate PET/MR To establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer * comparison of findings on PET/MR, MRI and PET/CT with pathological mapping after radical prostatectomy * outcome assessment: accuracy of PET/MR for localization and staging of prostate cancer compared with MRI only and PET/CT only To establish the imaging biomarker using PET/MR for early detection of recurrent prostate cancer * Recruiting 15 patients with recurrent prostate cancer treated by surgery, hormone, or radiation therapy * Recruiting 15 patients with treated prostate cancer without recurrence * PET/MR using 18F-choline with dedicated prostate MRI in all patients * PET/MR using 18F-FDG in all patients after 2-7 days * PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR * comparison of findings on PET/MR, MRI, and PET/CT with clinical data in two patient groups with or without recurrent prostate cancer * outcome assessment: accuracy of PET/MR for early detection and localization of recurrent prostate cancer compared with MRI only and PET/CT only
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | PET/MR | Multi-radiotracer PET/MR will be performed in patients with primary and recurrent prostate cancer |
Timeline
- Start date
- 2012-05-01
- Primary completion
- 2014-04-01
- Completion
- 2014-12-01
- First posted
- 2013-09-10
- Last updated
- 2013-12-05
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01938339. Inclusion in this directory is not an endorsement.