NCT01935791

Investigating Brown Adipose Tissue Activation in Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine what can activate brown adipose tissue (BAT).

Detailed description

We will investigate different stimuli (i.e. hormones) to determine which can stimulate BAT.

Conditions

• Metabolic Diseases

Interventions

Type	Name	Description
OTHER	Period 1 Visit 1 - Cold PET-CT Vehicle, Visit 2 -Warm PET-CT Vehicle	Temperature
DRUG	Period 1 Visit 1 - Cold PET-CT Vehicle, Visit 2 -Warm PET-CT Glucagon	Hormone
OTHER	Period 1 Visit 1 - Cold PET-CT Vehicle, no visit 2 as BAT negative	Temperature
DRUG	Period 2 - Visit 1 Warm Control vehicle, Visit 2 Warm Glucagon, Visit 3 Cold control	Hormone
DRUG	Period 2 - Visit 1 Warm Glucagon, Visit 2 Cold control , Visit 3 Warm control	Hormone
DRUG	Period 2 -Visit 1 cold control, Visit 2 warm control, Visit 3 Warm glucagon	hormone
DRUG	Period 2 -Visit 1 cold control, visit 2 warm glucagon, visit 3 warm control	hormone
DRUG	Period 2- Visit 1 Warm glucagon, visit 2 warm control, visit 3 cold control	hormone
DRUG	Period 2 - Visit 1 Warm control, visit 2 cold control, visit 3 warm glucagon	Hormone

Timeline

• Start date: 2013-07-01
• Primary completion: 2018-11-05
• Completion: 2018-11-05
• First posted: 2013-09-05
• Last updated: 2021-05-18
• Results posted: 2021-05-18

Locations

1 site across 1 country: United Kingdom