Trials / Completed
CompletedNCT01932476
Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes
Randomized Double-Masked Gluten Challenge to Evaluate Markers of Autoimmunity in Patients With Type-1 Diabetes and Celiac Disease After Oral Gluten Challenge
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 7 (actual)
- Sponsor
- Joslin Diabetes Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether the immune response causing celiac disease is related to the autoimmune response causing type-1 diabetes.
Detailed description
Participants meeting eligibility criteria will have blood collected before and after a three-day oral gluten challenge. This blood will be tested for biomarkers associated with islet autoimmunity and gluten-specific cellular immunity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Gluten Challenge | Three-day gluten containing dietary challenge. |
| DIETARY_SUPPLEMENT | Sham Challenge | Three-day sham (gluten free) dietary challenge |
Timeline
- Start date
- 2013-08-01
- Primary completion
- 2014-12-01
- Completion
- 2014-12-01
- First posted
- 2013-08-30
- Last updated
- 2017-04-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01932476. Inclusion in this directory is not an endorsement.