NCT01931215

Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: Benno Rehberg-Klug · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Analgesia after cesarean section is still not satisfactory for many women. Even if pain reduction is sufficient with the technique of intrathecal morphine injection, side effects such as nausea and pruritus are common. Since several years, an alternative technique has been studied, the "transversus abdominis plane (TAP)"-block. Here a local anesthetic is injected in the abdominal wall muscles, and this has been shown to give a similar analgesic effect compared to intrathecal morphine, with potentially less side effects. With this study, we want to evaluate if the TAP-block yields indeed less side effects when compared with intrathecal morphine. The study will be a prospective study with the patients randomized to either a group with intrathecal morphine or a group with TAP-block.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
OTHER	spinal anesthesia with intrathecal morphine	in addition to the standard spinal anesthesia drugs (bupivacaine and fentanyl), morphine is added
OTHER	TAP-block with ropivacaine and clonidine

Timeline

• Start date: 2013-09-01
• Primary completion: 2017-03-01
• Completion: 2017-08-28
• First posted: 2013-08-29
• Last updated: 2017-11-21

Locations

1 site across 1 country: Switzerland