NCT01927549

Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock

Prospective Randomized Multicenter Study Comparing Immediate Multivessel Revascularization by PCI Versus Culprit Lesion PCI With Staged Non-culprit Lesion Revascularization in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 706 (actual)
• Sponsor: University of Luebeck · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The study compares the therapies of instant multivessel balloon angioplasty plus stent implantation or the balloon angioplasty plus stent implantation of the infarct artery alone with any possible graduated later treatment of the other vessels in patients with acute myocardial infarction with cardioganic shock. The main study hypothesis is to explore if culprit vessel only PCI with potentially subsequent staged revascularization in comparison to immediate multivessel revascularization by PCI in patients with cardiogenic shock complicating acute myocardial infarction reduces the incidence of 30- day mortality and/or severe renal failure requiring renal replacement therapy.

Conditions

• Cardiogenic Shock
• Acute Myocardial Infarction
• Complications

Interventions

Type	Name	Description
PROCEDURE	Immediate multivessel PCI
PROCEDURE	Culprit Lesion only PCI

Timeline

• Start date: 2013-04-01
• Primary completion: 2017-07-01
• Completion: 2017-10-01
• First posted: 2013-08-22
• Last updated: 2017-11-09

Locations

3 sites across 1 country: Germany