Trials / Completed
CompletedNCT01925261
A Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees
A Randomized, Double-blind, Placebo-controlled, Multi-dose Phase 2 Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 in Subjects With Mild to Moderate Patello-Femoral Osteoarthritis Involving Both Knees
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- Sponsor
- OrthoTrophix, Inc · Industry
- Sex
- All
- Age
- 25 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This one-year study is designed to investigate the safety and efficacy of TPX-100, a 23-amino acid chondrogenic peptide, delivered by intra-articular injection, in regeneration of knee cartilage in subjects with bilateral osteoarthritis of the knee.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | TPX-100 50mg | |
| DRUG | TPX-100 100mg | |
| DRUG | TPX-100 200mg | |
| DRUG | TPX-100 20mg | |
| DRUG | Placebo |
Timeline
- Start date
- 2014-01-01
- Primary completion
- 2016-09-01
- Completion
- 2016-09-01
- First posted
- 2013-08-19
- Last updated
- 2017-04-21
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01925261. Inclusion in this directory is not an endorsement.