NCT01925079

Intensive Education on Lipid Management

A Randomized and Controlled Study About the Impact of Intensive Education on Lipid Management in Patients With Acute Coronary Syndrome in China

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,568 (estimated)
• Sponsor: Junbo Ge · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Among the patients with coronary heart disease, those with ACS (acute coronary syndrome) are extremely high-risk patients. Therefore, management outside hospital, especially the regular administration of drugs, is vital to prevent the recurrence of cardiovascular events. However, most patients often fail to stay on a long-term administration regimen, especially the administration of statins. According to the statistics, the average duration adhered with statin in patients with ACS is less than 3 months, use of statin at hospital discharge was only 80% and 65% in 6 month, with a very low LDL-C control rate (about 11% at 6 months), which poses a threat to the recurrence rate of cardiovascular events in patients with ACS. It was found in previous studies that there were many factors influencing patients' compliance, in which patients' refusing to take medicine accounted for a higher proportion. It suggests that patient had not recognized the importance of long-term administration. Therefore, it is extremely important for physicians to strengthen patient education and regular follow-up visits during disease management. Moreover, the effectiveness of patient education during chronic disease management has already been proved in some studies abroad, and the interventional effect of multiple patient education process outweighs that of single approach education. Thus, we intend to conduct a randomized and controlled study to explore the effect of multi-channel intensive patient education on LDL-C target achieving rate and statin adherence in patients with ACS in China.

Conditions

• Acute Coronary Syndrome

Interventions

Type	Name	Description
BEHAVIORAL	Intensive Education	Statin Treatment：The investigator will be suggested to increase the dose of atorvastatin according to guideline if a patient's LDL-C does not achieve target level. Patient education: 1. Routine education at discharge. 2. 4 education brochures will be delivered to patients. 3. Calendar with healthy tips will be delivered to patients before discharge. 4. A follow-up brochure with medical expert letter. 5. A total of 24 specific short messages for ACS will be developed and sent to patients (one short message per week). 6. Telephone follow ups will be performed according to a standard communication document. At discharge, patients will be given a brochure for future follow up.
OTHER	Control	Statin Treatment：The recommended dosage of atorvastatin will be adjusted at the physician's discretion. Patient education: 1. Routine education at discharge. 2. A follow-up brochure without medical expert letter. At discharge, patients will be given a brochure for future follow up.

Timeline

• Start date: 2013-08-01
• Primary completion: 2015-02-01
• Completion: 2015-06-01
• First posted: 2013-08-19
• Last updated: 2013-08-20

Locations

5 sites across 1 country: China