NCT01922713

Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women

Effect of Daily Consumption of β-carotene Biofortified Maize on Milk Retinol Concentration in Lactating Zambian Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 149 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to determine whether daily consumption of beta-carotene biofortified maize will increase breast milk retinol concentration in lactating Zambian women.

Detailed description

Lactating women were randomly assigned to one of three intervention groups to receive 6d/wk for 3 wk either 1) provitamin A biofortified orange maize and a corn oil capsule, 2) white maize and a vitamin A capsule, or 3) white maize and a corn oil capsule. The 'orange maize' and 'vitamin A' groups received \~600 ug RAE/d as provitamin A biofortified maize or retinyl palmitate, respectively. The 'white maize' group was a negative control group that did not receive any supplemental vitamin A.

Conditions

• Vitamin A Deficiency

Interventions

Type	Name	Description
OTHER	white maize and a corn oil capsule	\~ 0 ug RAE/d
OTHER	orange maize and a corn oil capsule	\~600 ug RAE/d
OTHER	white maize and a vitamin A capsule	600 ug RAE/d

Timeline

• Start date: 2013-10-01
• Primary completion: 2013-12-01
• Completion: 2014-12-01
• First posted: 2013-08-14
• Last updated: 2015-01-26

Locations

1 site across 1 country: Zambia