Clinical Trials Directory

Trials / Completed

CompletedNCT01922128

Safety Study of a Topical Treatment for Dry Age Related Macular Degeneration

A Phase 1 Randomized, Double-masked, Vehicle-controlled, Dose Escalation Study of the Ocular Safety and Tolerability of MC-1101 in Medically Stable Individuals

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
20 (actual)
Sponsor
MacuCLEAR, Inc. · Industry
Sex
All
Age
50 Years – 85 Years
Healthy volunteers
Accepted

Summary

Study to evaluate the safety and tolerability of MC-1101, a potential topical treatment for non-edxudative age Related Macular Degeneration (AMD) in medically stable individuals.

Detailed description

MC-1101 is a topical version of a previously approved anti-hypertensive drug that is intended to increase choroidal blood flow. * A reduction of choroidal blood flow has been identified in patients with AMD * This study will evaluate 0.5% and 1.0% potencies of MC-1101 delivered 2X per day.

Conditions

Interventions

TypeNameDescription
DRUGMC-1101, PlaceboOne drop 0.5%; MC-1101; One drop 1.0% MC-1101, One drop Placebo

Timeline

Start date
2013-09-01
Primary completion
2013-11-01
Completion
2013-12-01
First posted
2013-08-14
Last updated
2014-04-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01922128. Inclusion in this directory is not an endorsement.