NCT01921582

A Comparison of Methylphenidate and Cognitive Behavioural Therapy for the Treatment of Binge Eating Disorder

A Randomized Comparison of Osmotic Release Oral System Methylphenidate and Cognitive Behavioural Therapy for the Treatment of Obese Patients With Binge Eating Disorder

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 51 (actual)
• Sponsor: Centre for Addiction and Mental Health · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether methylphenidate is effective in the treatment of binge eating disorder, in a randomized controlled trial extended release methylphenidate versus cognitive behavioral therapy for binge eating disorder in overweight or obese adult females.

Detailed description

Fifty-six adult female outpatients with binge eating disorder will receive 12 weeks of methylphenidate (dosage 18-72 mg) or 12 sessions of manualized cognitive behavioral therapy. Participants will complete interviewer-rated and self-report measures of eating, mood, attention, and personality features before treatment, after 6 weeks of treatment, immediately after treatment is completed, and 3 months after treatment is completed.

Conditions

• Binge-Eating Disorder

Interventions

Type	Name	Description
DRUG	Methylphenidate	* Weekly appointments with study psychiatrists for the first four weeks, and then biweekly appointments for the last eight weeks. * Intervention will consist of medication as well as components of "Med-Plus" treatment (e.g., medication management, general support, and compliance enhancement strategies).
BEHAVIORAL	Cognitive Behavioral Therapy	Cognitive Behavior Therapy will include three phases: * Phase 1 undertakes to eliminate binge episodes and introduce a 'regular' pattern of eating; * Phase 2 aims to reduce food intake and restructure eating-related cognitions; * Phase 3 focuses upon relapse prevention

Timeline

• Start date: 2013-08-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2013-08-13
• Last updated: 2017-02-06

Locations

1 site across 1 country: Canada