NCT01921010

Benefit of Elevation of HDL-C in Women

Benefit of Elevation of HDL-cholesterol/Triglyceride Lowering on Cardiovascular Outcomes in Women

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Cedars-Sinai Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The combination of HDL-C elevation, lowering of triglycerides and further LDL-C reduction accomplished by the addition of niacin to statin medication would improve endothelial function as compared to LDL-C reduction alone in patients with and without coronary artery disease and the combination of low HDL-C/high triglycerides. The combination of lipid lowering therapy would have beneficial effects on markers of inflammation. These benefits would be particularly evident in women.

Conditions

• Cardiovascular Outcomes

Interventions

Type	Name	Description
DRUG	Niaspan	See Arm Description
DRUG	Placebo	See Arm Description

Timeline

• Start date: 2003-06-01
• Primary completion: 2005-06-01
• Completion: 2005-06-01
• First posted: 2013-08-13
• Last updated: 2019-04-23

Locations

1 site across 1 country: United States