Clinical Trials Directory

Trials / Completed

CompletedNCT01919827

Study of Autologous Mesenchymal Stem Cells to Treat Idiopathic Pulmonary Fibrosis

Treatment of Idiopathic Pulmonary Fibrosis With Bone Marrow Derived Mesenchymal Stem Cells

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
17 (actual)
Sponsor
Clinica Universidad de Navarra, Universidad de Navarra · Academic / Other
Sex
All
Age
30 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Clinical Trial Phase I, open, multicentric, non randomized, study with escalating doses, to evaluate the safety and feasibility of treatment with mesenchymal stem cells in patients with diagnosis of idiopathic pulmonary fibrosis. Primary endpoint: The aim is to evaluate the safety and feasibility of the endobronchial administration of mesenchymal autolog stem cells derived from bone marrow (BM-MSC)in patients with mild-to-moderate idiopathic pulmonary fibrosis. Secondary endpoint:Assess the possible effect of the infusion of BM-MSC in stopping the fall of pulmonary function in patients with mild-to-moderate idiopathic pulmonary fibrosis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALEndobronchial infusion of adult mesenchymal stem cells
BIOLOGICALAutologous mesenchymal stem cells derived from bone marrow

Timeline

Start date
2013-03-01
Primary completion
2018-05-01
Completion
2018-05-01
First posted
2013-08-09
Last updated
2018-05-03

Locations

2 sites across 1 country: Spain

Source: ClinicalTrials.gov record NCT01919827. Inclusion in this directory is not an endorsement.