Trials / Active Not Recruiting
Active Not RecruitingNCT01918527
Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer
- Status
- Active Not Recruiting
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 250 (actual)
- Sponsor
- Vejle Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare 3 cycles of neoadjuvant (preoperative) chemotherapy + operation with the standard treatment of locally advanced colon cancer, which is operation + 8 cycles of (adjuvant) chemotherapy. Patients receiving neoadjuvant chemotherapy may not need adjuvant chemotherapy after the operation and, if this is the case, they will be spared of 5 cycles of chemotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Capecitabine | Orally on days 1-14: 2000 mg/m2/day q3w |
| DRUG | Oxaliplatin | Intravenously on day 1: 130 mg/m2 q3w |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2023-06-01
- Completion
- 2026-06-01
- First posted
- 2013-08-07
- Last updated
- 2026-03-10
Locations
9 sites across 3 countries: Denmark, Norway, Sweden
Source: ClinicalTrials.gov record NCT01918527. Inclusion in this directory is not an endorsement.