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Trials / Completed

CompletedNCT01918462

Protective Immune Mechanisms in Alcoholic Hepatitis

Status
Completed
Phase
Study type
Observational
Enrollment
51 (actual)
Sponsor
University of Aarhus · Academic / Other
Sex
All
Age
18 Years – 69 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to investigate the production, effects and interactions of the hepato-protective cytokine interleukine (IL)-22 in patients with alcoholic hepatitis.

Detailed description

The investigators will study hepatic biopsies from patients with alcoholic hepatitis. In these biopsies, the investigators will assess the production of IL-22 and which cells produce the cytokine. The investigators will study the expression of the IL-22 receptor and also the production of the IL-22 binding protein, which can inhibit the actions of the cytokine.

Conditions

Timeline

Start date
2013-04-01
Primary completion
2018-04-20
Completion
2018-04-20
First posted
2013-08-07
Last updated
2021-04-29

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT01918462. Inclusion in this directory is not an endorsement.

Protective Immune Mechanisms in Alcoholic Hepatitis (NCT01918462) · Clinical Trials Directory