NCT01915667

Oral Bioavailability of Two Solid Formulations of GLPG0634

Bioavailability Study Comparing Two Solid Oral Formulations of GLPG0634 in Healthy Male Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Galapagos NV · Industry
• Sex: Male
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to evaluate the amount of compound present in the blood (relative bioavailability) after a single administration of GLPG0634 as a tablet versus a capsule in fasted conditions in male healthy subjects. Also, the effect of food on the bioavailability of the tablet formulation will be studied as well as the safety and tolerability of single oral doses of GLPG0634 given either as capsule or tablet.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	200 mg GLPG0634 as capsules, fasted	single oral dose of 200 mg GLPG0634 given as capsules in fasted condition
DRUG	200 mg GLPG0634 as tablets, fasted	single oral dose of 200 mg GLPG0634 given as tablets in fasted condition
DRUG	200 mg GLPG0634 as tablets, fed	single oral dose of 200 mg GLPG0634 given as tablets in fed condition

Timeline

• Start date: 2013-07-01
• Primary completion: 2013-09-01
• Completion: 2013-09-01
• First posted: 2013-08-05
• Last updated: 2013-09-17

Locations

1 site across 1 country: Belgium