Trials / Recruiting
RecruitingNCT01913938
Hemophagocytosis in Critically Ill Adult Patients
Hemophagocytosis in Critically Ill Adult Patients With Cytopenias
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- University of Ulm · Academic / Other
- Sex
- All
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to find out whether non-responsiveness to therapeutic recombinant human granulocyte colony-stimulation factor (rhG-CSF) is associated with hemophagocytosis in critically ill adult patients with cytopenias.
Detailed description
In children with bi- or pancytopenia, hemophagocytosis is known as life-threatening hemophagocytic lymphohistiocytosis (HLH). The purpose of the study is to find out whether adult patients with bicytopenia or pancytopenia fulfilling the clinical HLH criteria used in children reflect life-threatening hemophagocytosis and whether hemophagocytosis is associated with responsiveness to recombinant human granulocyte colony-stimulation factor (rhG-CSF) or not.
Conditions
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2025-07-01
- Completion
- 2026-12-01
- First posted
- 2013-08-01
- Last updated
- 2024-01-17
Locations
2 sites across 1 country: Germany
Source: ClinicalTrials.gov record NCT01913938. Inclusion in this directory is not an endorsement.