NCT01910779

Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks

Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks (OPTIMA Trial).

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 154 (estimated)
• Sponsor: Maria Vittoria Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Use of higher energy doses (120-150 J) may not offer additional benefits and higher success rate compared with low to moderate initial energy (100-120 J) of biphasic shock for atrial fibrillation cardioversion. In this prospective open-label randomized trial consecutive patients with AF and candidate to AF electrical cardioversion will be randomized to receive 100J or 120 J as initial dose of biphasic shock. Patients will be also randomized in each group to anterolateral or postero-anteriore placement of defibrillator electrodes.

Detailed description

Open-label randomized trial to assess the efficacy of alternative initial biphasic shocks (100 versus 120 J) for cardioversion of atrial fibrillation including alternative option for electrode placement (anterolateral or postero-anterior in each group).

Conditions

• Atrial Fibrillation
• Cardioversion

Interventions

Type	Name	Description
PROCEDURE	100 joule as first biphasic shock energy
PROCEDURE	120 joule as first biphasic shock energy

Timeline

• Start date: 2013-05-01
• Primary completion: 2014-03-01
• Completion: 2014-04-01
• First posted: 2013-07-30
• Last updated: 2013-07-30

Locations

1 site across 1 country: Italy