Clinical Trials Directory

Trials / Completed

CompletedNCT01908426

Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
707 (actual)
Sponsor
Exelixis · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the effect of Cabozantinib (XL184) compared with placebo on overall survival in subjects with advanced hepatocellular carcinoma who have received prior sorafenib.

Conditions

Interventions

TypeNameDescription
DRUGCabozantinib tablets
DRUGPlacebo tablets

Timeline

Start date
2013-09-26
Primary completion
2017-10-16
Completion
2021-01-12
First posted
2013-07-25
Last updated
2021-05-06
Results posted
2019-03-01

Locations

104 sites across 19 countries: United States, Australia, Belgium, Canada, France, Germany, Hong Kong, Ireland, Italy, Netherlands, New Zealand, Poland, Romania, Singapore, South Korea, Spain, Taiwan, Turkey (Türkiye), United Kingdom

Source: ClinicalTrials.gov record NCT01908426. Inclusion in this directory is not an endorsement.