NCT01907061

Acute Renal Failure Post Liver Transplantation

Acute Renal Failure Post Liver Transplantation: The Role of Cytokines and Oxidative Stress

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Baylor Research Institute · Academic / Other
• Sex: All
• Age: 18 Years – 71 Years
• Healthy volunteers: Not accepted

Summary

Trial to test the effect of administering N-acetylcysteine on cytokines and markers of oxidant stress and the incidence of acute renal failure post liver tranplant

Detailed description

1. To determine levels of pro-inflammatory cytokines and oxidative stress markers in liver transplant patients during post-transplant period 2. To correlate changes in pro-inflammatory cytokines and markers of oxidative stress to acute renal failure and acute rejection 3. To determine the impact of using N-acetylcysteine on cytokines and markers of oxidative stress and the incidence of acute renal failure post liver transplantation

Conditions

• Acute Renal Failure

Interventions

Type	Name	Description
DRUG	N-acetylcysteine	drug will be administered via IV,NG
DRUG	Placebo	placebo or NAC will be given

Timeline

• Start date: 2007-07-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2013-07-24
• Last updated: 2020-02-21

Locations

1 site across 1 country: United States