NCT01905280

Ridge Preservation Comparing 2 Membranes

Ridge Preservation Comparing the Clinical and Histologic Healing of a PTFE Non-resorbable Membrane Versus an Acellular Dermal Matrix Allograft Plus a Facial Overaly Bovine Xenograft.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: University of Louisville · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the clinical and histologic outcomes for acellular dermal matrix and a nonresorbable membrane to determine if either provides a significant therapeutic advantage. The hypothesis is that there will be no difference in crestal ridge width between the two treatments.

Detailed description

30 patients will be selected that meet the following criteria: Inclusion Criteria 1. Have one non-molar tooth requiring extraction that will be replaced by a dental implant. The site must be bordered by at least one tooth. 2. Healthy male or female who is at least 18 years old. 3. Patients must sign an informed consent approved by the University of Louisville Human Studies Committee. Exclusion Criteria 1. Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium. 2. Presence or history of osteonecrosis of jaws. 3. Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration. 4. Patients who have been treated with oral bisphosphonates for more than three years. 5. Patients with an allergy to any material or medication used in the study. 6. Patients who need prophylactic antibiotics. 7. Previous head and neck radiation therapy. 8. Chemotherapy in the previous 12 months. 9. Patients on long term NSAID or steroid therapy. 10. Pregnant patients.

Conditions

• Alveolar Ridge Deficiency

Interventions

Type	Name	Description
PROCEDURE	Non-resorbable membrane	The ridge preservation graft will be covered with a non-resorbable PTFE membrane during the surgery.
PROCEDURE	Acellular dermal matrix	The ridge preservation graft will be covered with an acellular dermal matrix allograft during the surgery.

Timeline

• Start date: 2013-09-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2013-07-23
• Last updated: 2016-12-08

Locations

1 site across 1 country: United States