NCT01903941

Anti-inflammatory Effect of Aerobic Exercise in Individual With Increased Cardiovascular Risk

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 68 (actual)
• Sponsor: Escola Bahiana de Medicina e Saude Publica · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Aerobic physical activity attenuates systemic inflammatory activity in individuals with cardiovascular risk.

Detailed description

Background: Observational studies suggest that exercise has anti-inflammatory effect, however this idea has not been definitively confirmed by randomized clinical trials. Objective: To test the hypothesis that aerobic exercise attenuates systemic inflammatory activity in individuals with cardiovascular risk. Methods: Randomized controlled trial, which included 68 sedentary individuals, with at least two risk factors for coronary heart disease or established cardiovascular disease. The volunteers were randomized to 3 months of supervised aerobic training or just advice when healthy lifestyles. C-reactive protein (CRP) was measured by the method of high sensitivity before and after 3 months of intervention.

Conditions

• Inflammation

Interventions

Type	Name	Description
BEHAVIORAL	Aerobic Exercise
BEHAVIORAL	Only Counseling

Timeline

• Start date: 2006-12-01
• Primary completion: 2008-04-01
• Completion: 2008-04-01
• First posted: 2013-07-19
• Last updated: 2013-07-19