NCT01901549

Renal Denervation in Patients After Acute Coronary Syndrome

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Meshalkin Research Institute of Pathology of Circulation · Network
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study is aimed to evaluate the effect of renal denervation to decreasing blood pressure and left ventricle remodeling progression in patients after acute coronary syndrome.

Conditions

• Acute Coronary Syndrome
• Arterial Hypertension

Interventions

Type	Name	Description
PROCEDURE	Renal denervation	The treatment catheter is introduced into each renal artery and is applied discrete, radiofrequency ablations lasting up to 2 min each and of 8 watts or less to obtain up to six ablations separated both longitudinally and rotationally within each renal artery. During ablation, the catheter system monitored tip temperature and impedance, altering radiofrequency energy delivery in response to a predetermined algorithm. After the procedure the control arterial angiogram should be done.
DRUG	Metoprolol	Beta-blockers. Optimal mediсal therapy will be assigned according to ACS and STE guidelines.
DRUG	Lisinopril	ACE inhibitors. Optimal mediсal therapy will be assigned according to ACS and STE guidelines.

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-06-01
• Completion: 2016-06-01
• First posted: 2013-07-17
• Last updated: 2015-09-23

Locations

1 site across 1 country: Russia