Trials / Completed
CompletedNCT01901497
Pharmacokinetics of Nebulized Amikacin in Non Invasive Ventilated Healthy Volunteers.
Comparison of Pharmacokinetics of Amikacin Administered by Three Vibrating Mesh Nebulizers in Healthy Volunteers
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 7 (actual)
- Sponsor
- University Hospital St Luc, Brussels · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of the study is to compare the pharmacokinetics of nebulized amikacin administered with three vibrating mesh nebulizers coupled with a single limb circuit bilevel ventilator in healthy volunteers. Following our previous in vitro study, our hypotheses are that the pharmacokinetics varies among the devices tested and that a most efficient device can be identified.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Nebulizer | 500 mg/4 mL Amikacin nebulized using vibrating mesh nebulizer associated with a single limb bilevel ventilator. The nebulizations are considered as finished when there is no visible evidence of nebulization for a period of 30 seconds. |
Timeline
- Start date
- 2013-07-01
- Primary completion
- 2015-06-01
- Completion
- 2016-01-01
- First posted
- 2013-07-17
- Last updated
- 2016-02-01
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT01901497. Inclusion in this directory is not an endorsement.