NCT01900366

Pilot Study for Noninvasive Spectroscopic Detection of Adipose Tissue Inflammation in Obesity

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 14 (actual)
• Sponsor: Rockefeller University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This study will test the potential of two techniques using light properties of adipose tissue to diagnose crown-like structures and inflammation to be compared with pathologic examination of adipose tissue biopsies from ongoing clinical studies.

Detailed description

Adipose tissue (fat) inflammation is emerging as an important harbinger of disease development including Type 2 diabetes, heart disease and potentially cancer. The hallmark feature of adipose tissue inflammation is the crown-like structure, a dying fat cell surrounded by immune cells attempting to clear the damage. Current methods for detecting adipose tissue inflammation rely on invasive procedures such as fat biopsies. We propose developing methods that use the light reflection properties of inflamed adipose tissue as a potential non-invasive method to detect adipose tissue inflammation.

Conditions

• Obesity

Interventions

Type	Name	Description
PROCEDURE	Fat Biopsy	Fat biopsy

Timeline

• Start date: 2013-08-01
• Primary completion: 2016-08-01
• Completion: 2016-08-01
• First posted: 2013-07-16
• Last updated: 2016-09-19

Locations

1 site across 1 country: United States