NCT01899885

Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,200 (actual)
• Sponsor: Hvidovre University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to implement an optimized perioperative course for patients undergoing acute high-risk abdominal surgery in order to improve the outcome. The optimized perioperative course consists of a number of interventions carried out before, during and after surgery.

Detailed description

Emergency surgery is associated with high mortality rates, post-operative complications and prolonged duration of hospital admission. The investigators will implement a multidisciplinary optimized perioperative course consisting of a number of interventions carried out before, during and after surgery. Hypothesis: An optimized perioperative course will reduce the 30-day mortality in emergency abdominal surgery patients. The investigators will do a post-hoc analysis of the data registered.

Conditions

• Perforated Viscus
• Intestinal Obstruction

Interventions

Type	Name	Description
PROCEDURE	AHA (Acute Highrisk Abdominalsurgery): Optimized Course	optimized course: Intervention before, during and after abdominal surgery. Focus on fast track with multimodal standardized intervention: 1. standardized preparing for surgery including high dose antibiotics and epidural analgesia etc. and transfer to intermediate care before surgery (the post-anaesthesia care unit) 2. GDT-LiDCO fluid management pre-, per- and postoperative 3. Postoperative triage to 24 hour intermediate care based on ASA score and Surgical Apgar Score 4. Focus on early mobilization, fysiotherapy and optimal nutrition postoperatively

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-05-01
• Completion: 2015-06-01
• First posted: 2013-07-16
• Last updated: 2015-06-12

Locations

1 site across 1 country: Denmark