NCT01898052

The Efficacy of Periarticular Single Drug Compared With Multimodal Drug Injection in Controlling Pain After TKA

A Comparative Study on the Efficacy of Periarticular Single Anesthetic Drug Compared With Multimodal Drug Injection in Controlling Pain After Total Knee Arthroplasty: A Double Blinded Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Thammasat University · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the periarticular multimodal drug injection has more efficacy for controlling pain after TKA than single anaesthetic drug injection.

Detailed description

Many studies have to determine the efficacy of periarticular multimodal drug injection or single local anaesthetic drug comparing with placebo for pain controlled in TKA. But in this study would like to determine which one of both drugs are more efficacy. In multimodal drug injection consist of levobupivacaine, morphine, ketorolac and epinephrine while single anaesthetic drug has levobupivacaine and epinephrine.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	single anaesthetic drug	inject periarticular tissue of the knee after implantation
DRUG	multimodal drug injection	inject periarticular tissue of the knee

Timeline

• Start date: 2012-10-01
• Primary completion: 2014-02-01
• Completion: 2014-03-01
• First posted: 2013-07-12
• Last updated: 2014-04-02

Locations

1 site across 1 country: Thailand