Clinical Trials Directory

Trials / Completed

CompletedNCT01896323

CC-223 and Ketoconazole Drug-Drug Interaction Study

An Open-Label, Two-Period, Fixed-Sequence Study to Evaluate the Effect of Multiple Doses of Ketoconazole on the Single Dose Pharmacokinetics of CC-223 in Healthy Adult Male Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Celgene · Industry
Sex
Male
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

This is a single-center open-label study to compare how CC-223 (the study drug being investigated) interacts with the drug ketoconazole.

Detailed description

This is a 2 period study, which lasts about 6 weeks long. About 14 males will be entered into the study, during which they will receive the study drug (a single dose of 20 mg CC-223) 400 mg ketoconazole.

Conditions

Interventions

TypeNameDescription
DRUGCC-223CC-223 20 mg tablets
DRUGKetoconazoleKetoconazole 400 mg tablets

Timeline

Start date
2013-07-01
Primary completion
2013-08-01
Completion
2013-08-01
First posted
2013-07-11
Last updated
2019-11-12

Source: ClinicalTrials.gov record NCT01896323. Inclusion in this directory is not an endorsement.

CC-223 and Ketoconazole Drug-Drug Interaction Study (NCT01896323) · Clinical Trials Directory