NCT01894737

The Effect of Creatine on Muscle Loss

The Effect of Creatine Supplementation on Muscle Loss During Immobilisation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.

Detailed description

Seven days of one-legged knee immobilisation in young subjects with creatine or Placebo supplementation. A randomly selected leg is immobilized for seven days. Muscle mass and strength will be determined and muscle biopsies will be collected before and immediately after immobilisation. A week after the cast is removed we will assess any differences in recovery between intervention groups.

Conditions

• Muscle Loss

Interventions

Type	Name	Description
OTHER	Placebo supplementation	Seven days of one-legged knee immobilisation with placebo supplementation
OTHER	Creatine supplementation	Seven days of one-legged knee immobilisation with creatine supplementation.

Timeline

• Start date: 2013-10-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2013-07-10
• Last updated: 2015-08-31

Locations

1 site across 1 country: Netherlands