NCT01894295

Assessment Vitamin D Analogues Intake Pathways on the Proteins Which Involved in Metabolic Rate in Obese Subjects

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (estimated)
• Sponsor: Tehran University of Medical Sciences · Academic / Other
• Sex: All
• Age: 22 Years – 52 Years
• Healthy volunteers: Accepted

Summary

The aim of this double blind clinical trial study is to investigate whether alphacalcidol treatment in obese subjects can affect the resting metabolic rate. Moreover, the investigators will evaluate the pathways of Nesfatin-1, Peroxisome proliferator-activated receptor gamma (PPARγ) and eroxisome proliferator-activated receptor- coactivator-1 α (PGC1α) protein which may lead to change in metabic rate following treatment with either alphacalcidol or placebo.

Conditions

• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo	Corn oil pearl Capsules 1 gram; were given to the intervention group once a day for 8 weeks
DIETARY_SUPPLEMENT	Vitamin D analogue	1-α hydroxyvitamin D3 dose 0.25, 0.5 and 1 microgram were given to the intervention group once a day for 8 weeks

Timeline

• Start date: 2012-06-01
• Primary completion: 2013-06-01
• Completion: 2013-09-01
• First posted: 2013-07-10
• Last updated: 2013-07-10

Locations

1 site across 1 country: Iran