Clinical Trials Directory

Trials / Completed

CompletedNCT01892163

Multicentre Randomised Clinical Trial Comparing Fixed vs Pro re Nata (PRN) Dosing of 700 μg Dexamethasone

A Multicentre Prospective Open-label Randomised Clinical Trial Comparing the Efficacy of Fixed Versus PRN Dosing of 700 μg Dexamethasone Posterior Segment Drug Delivery System (Ozurdex) in Patients With Refractory Diabetic Macular Oedema

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
100 (actual)
Sponsor
Moorfields Eye Hospital NHS Foundation Trust · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Multicentre randomized controlled trial to evaluate whether 5 monthly fixed dosing of 700 µg Dexamethasone Posterior Segment Drug Delivery System (Ozurdex) is as efficacious as Optical coherence tomography (OCT)-guided PRN dosing in patients with refractory diabetic macular edema.

Conditions

Interventions

TypeNameDescription
DEVICEOzurdexDexamethasone implant (Ozurdex)

Timeline

Start date
2013-03-01
Primary completion
2014-12-01
Completion
2014-12-01
First posted
2013-07-04
Last updated
2017-02-23
Results posted
2017-02-23

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT01892163. Inclusion in this directory is not an endorsement.