NCT01890564

Modes of Ventilation During Laparoscopic Bariatric Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Joseph D. Tobias · Academic / Other
• Sex: All
• Age: 14 Years – 20 Years
• Healthy volunteers: Not accepted

Summary

During minimally invasive surgery, a pneumoperitoneum is created to facilitate surgical visualization. Although effective in facilitating the procedure, there are respiratory consequences of the pneumoperitoneum, which significantly increases intra-abdominal pressure (IAP) up to 20 cmH2O. The increased IAP can decrease functional residual capacity and increase closing capacity resulting in increased resistance, decreased compliance, and increased ventilation-perfusion mismatch. In a randomized, cross-over design, this study will evaluate in sequential order, 3 modes of ventilation during laparoscopic bariatric surgery to determine which is better able to support oxygenation and ventilation while limiting the peak inflating pressure (PIP).

Conditions

• Bariatric Surgery

Interventions

Type	Name	Description
OTHER	Pressure controlled ventilation	For pressure controlled ventilation, the peak inflating pressure (PIP) is set for each tidal breath.
OTHER	Volume controlled ventilation	For volume controlled ventilation, the tidal volume is set.
OTHER	PRVC ventilation	Pressure-regulated, volume-controlled (PRVC) is an auto-regulated pressure-controlled mode of mechanical ventilation with a user-selected tidal volume target.

Timeline

• Start date: 2013-06-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2013-07-02
• Last updated: 2014-04-01

Locations

1 site across 1 country: United States