Trials / Completed
CompletedNCT01888744
Preimplantation Genetic Diagnosis (PGD) With Gonadotropin-releasing Hormone (GnRH) Agonist Versus Antagonist
The Effect of the Type of Ovarian Stimulation Protocol on PGD Results: a Prospective Randomised Trial
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 120 (actual)
- Sponsor
- Universitair Ziekenhuis Brussel · Academic / Other
- Sex
- Female
- Age
- 18 Years – 39 Years
- Healthy volunteers
- Not accepted
Summary
The aim of our study is to define the optimal ovarian stimulation protocol concerning PGD and for this reason we plan a randomized controlled trial (RCT) comparing gonadotropin-releasing hormone (GnRH) agonist protocol versus GnRH antagonist protocol. The follicle stimulating hormone (FSH) preparation in both arms will be highly purified FSH (Menopur®).
Detailed description
Patients will be randomized at the outpatient clinic in two groups.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GnRH agonist | |
| DRUG | GnRH antagonist | |
| DRUG | hP-hMG | |
| DRUG | Human chorionic gonadotropin | induction of final oocyte maturation |
| DRUG | Progesterone |
Timeline
- Start date
- 2010-09-01
- Primary completion
- 2013-06-01
- Completion
- 2013-06-01
- First posted
- 2013-06-28
- Last updated
- 2013-06-28
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT01888744. Inclusion in this directory is not an endorsement.