NCT01886937

Studying the Effects of Phentermine on Eating Behavior

The Quantification of Ingestive Behavior

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: New York State Psychiatric Institute · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to determine whether one week of phentermine compared to placebo administration results in changes in food intake during a laboratory meal.

Detailed description

This study aims to explore whether short-term measures of eating behavior can be related to later, longer-term weight loss. In a double-blind, randomized fashion, participants will be asked to take study medication for three weeks: one week of phentermine and two weeks of placebo. At the end of the first and third weeks, participants will be asked to participate in a range of eating behavior studies. Following this three-week, double-blind phase, participants will be offered 6 months of open treatment for weight loss.

Conditions

• Obesity

Interventions

Type	Name	Description
DRUG	Phentermine	After 7 days of phentermine 37.5 mg administration, food intake should be less than after 14 days of placebo.
DRUG	placebo	Food intake as measured by a laboratory study should be greater after 7 days of placebo administration compared to seven days of phentermine administration.

Timeline

• Start date: 2012-07-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2013-06-26
• Last updated: 2017-07-31
• Results posted: 2017-07-31

Locations

1 site across 1 country: United States