NCT01883752

Goal Directed Fluid Management Based on Non-invasive Monitoring

Goal-Directed Fluid Management Based on Non- Invasive Monitoring of Pulse Oximeter-Derived Pleth Variability Index

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 334 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate whether goal directed fluid management using respiratory variations in the oxygen saturation by pulse oximetry (SpO2) waveform has potential to decrease postoperative complications and outcomes.

Detailed description

The aim of this study is to test the hypothesis that monitoring and minimizing the respiratory variations in the pulse oximeter waveform amplitude by volume loading has potential to decrease postoperative morbidity and length of stay in the hospital in patients undergoing routine, moderate-risk elective surgery. In this study the investigators will test the impact of hemodynamic optimization based on the respiratory variations in the plethysmographic waveform amplitude to decrease postoperative morbidity and length of stay in the hospital in patients undergoing routine, moderate-risk elective surgery. The primary outcome variable is the incidence of postoperative complications. Secondary outcome variables are the duration of hospital and ICU stays, postoperative mortality, and cost of surgery.

Conditions

• Postoperative Complication

Interventions

Type	Name	Description
PROCEDURE	Goal-directed Therapy group	Fluid administration is based on the respiratory variation in the pulse oximeter waveform

Timeline

• Start date: 2011-07-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2013-06-21
• Last updated: 2016-02-10

Locations

1 site across 1 country: United States