NCT01879514

Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropath

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Shanghai University of Traditional Chinese Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

IgA nephropathy(IgAN) is the highest incidence of kidney pathology in the primary nephropathy. In terms of differences in prognosis, severe IgA nephropathy,one of the most main primary renal disease,could cause the uremia. It will be significant that early indicators of prognosis and early intervention can be normalized and the scientific criteria for judging the efficacy of great clinical can be established. The subject based on the past study,literature research and various treatment will take the method of multi-center, double-blind, randomized, control to investigate the standard treatment of severe IgA nephropathy. Otherwise the uniformity and objectivity of Traditional Chinese Medicine (TCM) will be improved by the standardization of TCM research based on the epidemiological investigation and statistical analysis. The subject will determine the efficacy of more sensitive biomarkers and establish more scientific criteria for judging the effect with the application of urine proteomics and metabolomics technologies in order to operate in the formation of the standardization program of the treatment of severe IgA nephropathy with the Integrative medicine of TCM.

Conditions

• IgA Nephropathy

Interventions

Type	Name	Description
DRUG	Chinese Herb Prescription Granule plus prednisone	Chinese Herb Prescription Granule includes ZiBuGanShen Granule and BuShenTongLuo Granule
DRUG	Placebo	Placebo includes placebo of ZiBuGanShen Granule and placebo of BuShenTongLuo Granule

Timeline

• Start date: 2010-01-01
• Primary completion: 2013-12-01
• First posted: 2013-06-17
• Last updated: 2013-06-17

Locations

1 site across 1 country: China