NCT01873690

Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI)

A Randomized Controlled Trial Assessing the Efficacy of Antimicrobial Prophylaxis for Extracorporeal Shock Wave Lithotripsy on Reducing Urinary Tract Infection

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 360 (actual)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to test whether administering one dose of an antibiotic before a routine shock wave lithotripsy procedure is more effective at avoiding any urinary infections compared to not taking an antibiotic. This is an important topic to study because urinary tract infections are one of the most common complications after this procedure and there is no clear standard of care regarding the use of pre-procedure antibiotics. Our study results will benefit future patients either by decreasing the rate of infections or decreasing the use of unnecessary antibiotics.

Conditions

• Urolithiasis

Interventions

Type	Name	Description
DRUG	Ciprofloxacin	Once, 400 mg IV
DRUG	Placebo	5% Dextrose in water

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2013-06-10
• Last updated: 2016-02-08

Locations

1 site across 1 country: Canada