NCT01873664

Functional Magnetic Resonance Imaging Study of Jaw-tapping Movement on Memory Function

Brain Activity During Jaw Tapping Movement in Healthy Subjects and Mild Cognitive Impairment Patients Using Functional Magnetic Resonance Imaging

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Kyunghee University Medical Center · Academic / Other
• Sex: Female
• Age: 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine the possibility of using jaw-tapping training as a self-exercise for developing memory and preventing dementia in elderly subjects with memory disturbances using functional magnetic resonance imaging (fMRI).

Detailed description

Right-handed female volunteers over the age of 50 years with subjective memory complaints are included in the study. Volunteers with dentures, psychoactive medication, history of stroke, or other neurologic disorders are excluded. The protocol was approved by the Institutional Review Board of university-based hospital. After administering the Seoul Neuropsychological Screening Battery (SNSB), Mini-Mental State Examination (MMSE) scores above 24 and Clinical Dementia Rating Scale (CDR) scores of 0 are considered subjective memory complaints (SMC), and MMSE scores above 23 and CDR scores of 0.5 are considered MCI. All subjects undergo two MRI scans. After the first MRI, the subjects are trained to tap their jaws vertically at 1.6 Hz at home twice a day for 30 seconds every day during four weeks.

Conditions

• Memory Disturbances

Interventions

Type	Name	Description
BEHAVIORAL	Jaw-tapping	to tap their jaws vertically at 1.6 Hz at home twice a day for 30 seconds every day during four weeks.

Timeline

• Start date: 2009-05-01
• Primary completion: 2013-07-01
• Completion: 2013-07-01
• First posted: 2013-06-10
• Last updated: 2013-06-10

Locations

1 site across 1 country: South Korea