Trials / Completed
CompletedNCT01871909
Validation of Lower Body Negative Pressure (LBNP) Model of Human Hemorrhage in Trauma Patients
Validation of LBNP Model of Human Hemorrhage in Trauma Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 31 Days – 89 Years
- Healthy volunteers
- Not accepted
Summary
Lower body negative pressure (LBNP) is a laboratory model used to study hemorrhage in humans. The investigators hypothesize that the physiologic changes that occur with application of LBNP mimic those observed in bleeding and hemodynamically unstable trauma patients, and that LBNP is a truly valid model of human hemorrhage.
Detailed description
Specific aims: 1. Compare physiologic waveform data obtained from bleeding and hemodynamically unstable trauma patients to existing data collected from LBNP subjects. 2. Determine the accuracy of LBNP in approximating the physiologic changes that occur in bleeding and hemodynamically unstable trauma patients.
Conditions
Timeline
- Start date
- 2013-10-01
- Primary completion
- 2018-12-01
- Completion
- 2018-12-01
- First posted
- 2013-06-07
- Last updated
- 2019-10-08
Locations
3 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01871909. Inclusion in this directory is not an endorsement.